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Pyelonephritis is a kidney infection usually caused by bacteria that have traveled to the kidney from an infection in the bladder.

Women have more bladder infections (also called urinary tract infections) than men because the distance to the bladder from skin, where bacteria normally live, is quite short and direct.

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Coverage includes: clinical syndromes (organized by anatomic system/site of infection), pathogens (bacterial, fungal, mycobacterial, parasitic and viral), anti-infective agents (dosing, adverse effects, activity, pharmacology, interactions), specialized dosing tables and tools, calculators and preventative therapy, all evidence-based and extensively referenced.Most patients will be better served by first-line treatment with bismuth quadruple therapy or concomitant therapy consisting of a PPI, clarithromycin, amoxicillin, and metronidazole.When first-line therapy fails, a salvage regimen should avoid antibiotics that were previously used.Pyelonephritis and other forms of urinary tract infection increase the risk of premature delivery.A man is more likely to develop the problem if his prostate is enlarged, a common condition after age 50.

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